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氧氟沙星滴眼液和滴耳液的研制 被引量:15

Preparation and clinical application of ofloxacin eye-drops and ear-drops
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摘要 本文通过溶解度、稳定性、抑菌性实验,经过筛选,确定了氧氟沙星滴眼液和滴耳液的处方、制备方法和质控标准,并采用初均速法考察了两种制剂的稳定性。滴眼液和滴耳液的室温有效期分别为4.81年和6.55年。 he formula method of preparation and specifications of ofloxacin eye-drops and ear-drops was estabished according according to the study of solubility,stability,bacteriostatic and other tests.The stability of ofloxacin eye-drops and ear-drops was studied pri-marily using the initial average rate method.The shelflives of ofloxacin eye-drops and ear-drops at 25℃ were 4.81 and 6.55year.
出处 《中国医院药学杂志》 CAS CSCD 北大核心 1994年第9期405-406,共2页 Chinese Journal of Hospital Pharmacy
关键词 氧氟沙星 滴眼液 滴耳液 制备 ofloxacin,eye-drops,ear-drops
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参考文献1

  • 1庞贻慧,鲁纯素编写..药物稳定性预测方法[M].北京:人民卫生出版社,1984:238.

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