摘要
本文通过溶解度、稳定性、抑菌性实验,经过筛选,确定了氧氟沙星滴眼液和滴耳液的处方、制备方法和质控标准,并采用初均速法考察了两种制剂的稳定性。滴眼液和滴耳液的室温有效期分别为4.81年和6.55年。
he formula method of preparation and specifications of ofloxacin eye-drops and ear-drops was estabished according according to the study of solubility,stability,bacteriostatic and other tests.The stability of ofloxacin eye-drops and ear-drops was studied pri-marily using the initial average rate method.The shelflives of ofloxacin eye-drops and ear-drops at 25℃ were 4.81 and 6.55year.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1994年第9期405-406,共2页
Chinese Journal of Hospital Pharmacy