摘要
红细胞是一种天然的输送载体。红细胞经低渗透析膨胀和等渗透析重封，可包载ＳＯＤ蛋白质和多肽药物。实验结果表明，红细胞可有效地包载ＳＯＤ，其行为属简单的扩散过程，并符合一级吸收与消除二室动力学模型。
Peptides and proteins such as SOD can be entrapped into red blood cells(RBCs) -a kind of natural delivery carriers by hypotonic dialysis followed by resealing. Results indicate that encapsulation of SOD into RBCs is effective and that the process of encapsulation is a simple diffusion which can be described as a first-order two-compartment kinetics model.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1994年第7期309-311,共3页
Chinese Journal of Pharmaceuticals
