摘要
目的:检测NF κB、Ki6 7和Bcl 2在腺性膀胱炎中的表达,并分析NF κB与腺性膀胱炎的关系,以及NF κBP6 5、Ki6 7和Bcl 2的关系。方法:采用免疫组化SP法进行研究。结果:NF κBP6 5、Ki6 7和Bcl 2在2 4例腺性膀胱炎中的阳性表达率分别为70 .8%、5 4 .2 %、6 6 .7%。NF κB阳性表达率随腺性膀胱炎复发的增多而增高。结论:NF κB可能在腺性膀胱炎中起促进作用,可考虑将其作为评价腺性膀胱炎预后的参考指标。NF κB、Ki6 7和Bcl 2在腺性膀胱炎中的表达具有正相关性。
Objectives: To study the expression of NF-κB,Ki67 and Bcl-2 in cystitis glandularis and to find the relationship between NF-κB and cystitis glandularis.The relationship between NF-κB and ki67,NF-κB and Bcl- was also investigated.Methods: The expression of NF-κB,Ki67 and Bcl-2 in 24 cases of paraffin-embeded tissues of cystitis glandularis and 13 controlled samples was examined by SP immunohistochemistry. Resultes:The positive expression rate of NF-κBP65,Ki67 and Bcl-2 in cystitis glandularis were 70.8%,54.2% and 66.7% respectively.The high expression rate of NF-κB in cystitis glandularis was associated with high recurrence rate.Conclusions: It is deduced that NF-κB probably accelerates the progression of cystitis glandularis and its recurrence.It probably serves as a parameter to judage the prognosis of cystitis glandularis.There is a positive correlation between NF-κB and Ki67,NF-κB and Blc-2.
出处
《农垦医学》
2005年第1期4-6,共3页
Journal of Nongken Medicine
