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老年患者下呼吸道革兰阴性菌感染病原菌分布及耐药性分析 被引量:1

Distribution and drug resistance of gram-negative bacilli from lower respiratory tract in senile patients
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摘要 目的 了解老年患者下呼吸道革兰阴性菌感染常见病原菌的分布及耐药状况。方法 对我院2 0 0 2~2 0 0 3年老年患者痰液中分离出的4 6 8株革兰阴性菌选用14种常用抗生素进行药敏试验。结果 分离出的4 6 8株革兰阴性菌,主要为:铜绿假单胞菌114株,占2 4 .4 % ,肺炎克雷伯菌113株,占2 4 .1% ,鲍曼氏不动杆菌93株,占19.9% ,阴沟肠杆菌6 4株,占13.7% ,大肠埃希氏菌2 7株,占5 .8% ,嗜麦芽寡养单胞菌2 5株,占5 .3% ;耐药性分析显示,革兰阴性菌对临床常用抗生素的耐药率最低为亚胺培南,最高为氨苄西林,大部分细菌呈多重耐药。结论 老年患者下呼吸道革兰阴性菌耐药谱广,多重耐药严重。 Objective To explore the dist ri bution and drug resistance of Gram-negative bacilli from lower respiratory trac t in senile patients.Methods Drug-resistance test was perf ormed in 468 strains of Gram-negative bacilli by using 14 kinds of ordinary ant ibiotics from 2002 to 2003 year in our hospital.Results A to tal of 468 strains of Gram-negative bacilli were isolated from senile patients ’ sputum in the past two years,among them the most common pathogens were Pseudo monas aeruginosa(114 strains,24.4%),Klebsiella pneumoniae(113strains,24.1%),Acin etobacter baumanii(97 strains,19.9%),Enterobacter cloacae(64 strains,13.7),Esche richia coli(27 strains,5.8%),Stenotrophomonas maltophilia (25 strains,5.3%);In o ur surveillance,the highest sensitive to Gram-negative bacilli was imipenem,whi le the lowest was ampicillin.Most of strains were multi-drug resistant. Conclution Most of Gram-negative baciui from lover respiratory trac t are highly resistant to drugs,and have got resistance to many kinds of antibio tics.
出处 《中国临床保健杂志》 CAS 2005年第2期102-103,共2页 Chinese Journal of Clinical Healthcare
关键词 老年人 呼吸道感染 革兰阴性菌感染 抗药性 细菌 Aged(65+) Respiratory tract infections Gram-ne gative bacteriaial infections Drug Resistance,bacterial
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