摘要
目的 了解遗传与环境因素在癔症发病中的作用。 方法 以住院癔症病人为索引病例 ,调查其先天遗传因素及后天环境因素 ,并进行 1∶1病例对照。结果 癔症患者一、二、三级亲属的预期发病率分别为 2 .6 %、0 .6 6 %和 0 .4 4% ,癔症的遗传率为 30 .3% ,父亲年龄与子女患病之间的偏相关系数为 0 .70 4 ,癔症的发病与癔症家族史、季节、家庭暴力、家庭环境和父母养育方式等因素有关 ,癔症的每一亚型均有着其相同或不同的发病危险因素。结论 遗传因素在癔症的发病中起主导作用 ,环境因素是促发因素 ,癔症各亚型之间存在着发病机制的共性和差异。
Objective To explore the roles of genetic an d other family factors in causing hypochondriasis.Methods Hospitali zed cases of hypochondriasis were surveyed to detect the cogenital and acquired family factors,and contrasts were made between the same numbers of hypochondrias tic cases and non-hypochondriastic cases.Results The expectant r ates of incidence of the first-order,second-order and third-order relatives w ere 2.6%,0.66% and 0.44% respectively.The hereditary rate was 30.3%.The partial correlation index of the ages of fathoers and their children was 0.704.The occur rence of hypochondriasis was related to family history,seasons,family violence,f amily environment and the cultivation mode.Each subgroup has its own similar or different risk factors.Conclusion Hereditary factors play a leadi ng role while family environment an initiative role in causing hypochondriasis.T here exist similar and different pathogenic mechanisms between different subgrou ps.
出处
《临沂医学专科学校学报》
2005年第1期27-30,共4页
Journal of Linyi Medical College
基金
临沂市科技发展计划项目 (No .993 0 2 0 1)。
关键词
癔症
遗传学
环境因素
Hypochondriasis
Genetics
Environmental factors
