摘要
目的探讨金黄色葡萄球菌耐药特征,指导临床合理用药。方法使用美国BD公司PHOENIX100全自动细菌鉴定/药敏仪进行鉴定、K-B法药敏试验、B-内酰胺酶测试,并以“WHONET5”软件对数据进行分析处理。结果产B-内酰胺酶90株占53. 3%,MRSA占SA感染标本总数的60. 9%,MRSA耐药率介于8. 3%—95. 3%,本室未检出耐万古霉素、替考拉宁、呋喃妥因的菌株,耐药率低的抗生素有利福平、阿米卡星、氨苄西林/舒巴坦、阿莫西林/克拉维酸、头孢噻肟。耐药率高的有青霉素、苯唑青霉素、红霉素、SMZ、喹洛酮类等。结论金黄色葡萄球菌呈高度耐药性,万古霉素是治疗MRSA感染的首选抗生素,MRSA的耐药性应引起广泛关注。
Objective To acquire the information about the present resistance characteristics in Staphylococcus aureus.and to instruct rational application of antibiotics clinically. Methods 169 strains of Staphylococcus aureus ,The susceptibility testing and β-lactamase determination were performed for each of the 169 strains.The data from all of the tests were combined for analysis using WHONET 5 software .Results The ratio of MRSA to total Staphylococcus aureus isolates was 60. 9%, Both MRSA and MSSA were susceptibility to vancomycin. MRSA showed multireisistance to 15 of 18 antibiotics with rates ranging from 28% to 100%.Conclusion Staphylococcus aureus present high-level resistance .Vancomycin is the first choice antibiotics of MRSA infections,treating with MRSA should be emphasized.
出处
《川北医学院学报》
CAS
2005年第1期89-90,共2页
Journal of North Sichuan Medical College
