摘要
活动性十二指肠溃疡（ＤＵ）４６例（男性３３例、女性１３例，年龄４１±ｓ１１ａ），以奥美拉唑（Ｏｍｅ）２０ｍｇ，ｐｏ，ｑｄ，与３８例（男性２９例，女性９例，年龄４４±１２ａ）用法莫替丁（Ｆａｍ）４０ｍｇ，ｐｏｑｎ治疗作对比，疗程４ｗｋ。Ｏｍｅ组溃疡愈合率为９３％，Ｆ组为６１％，Ｐ＜０．０１。Ｏｍｅ组服药后１－２ｄ止痛者５７％，４ｄ内为１００％，Ｆａｍ组分别为２１％和６２％（Ｐ＜０．０１和Ｐ＜０．０５）。Ｏｍｅ疗效优于Ｆａｍ。
Forty-six patients with active duodenal ulcer(DU)(M33,F13;age 41±s 11 a)were treated with omeprazole(Ome) 20 mg,po,qd,while 38 patients(M29,F 9;age 44±12 a)were given famotidein(Fam) 40 mg,po,qn for 4 wk.The healing rate of DU was 93% in Ome group and 61%in the Fam group(P<0.01).Pain relieved 1-2 din 57% and 4 d in 100% of the patients in Ome group,but were 21% and 62% of the patients in Fam group,respectively(P<0.01 and P<005).Therefore,Ome is better than Fam.
出处
《新药与临床》
CSCD
北大核心
1994年第4期211-212,共2页
