摘要
目的:探讨颈动脉粥样硬化与冠心病及其危险因素的相关性。方法:超声检测191例可疑冠心病患者的颈动脉内中膜厚度(IMT)及斑块。取16个测量位点,即双侧颈总动脉、颈内动脉、颈外动脉及颈动脉窦的前壁和后壁。将患者按照造影结果分组,比较其动脉硬化指标。结果:颈动脉与冠状动脉有共同的危险因子,如增龄、血脂异常。冠心病组IMT明显大于对照组。多元回归分析表明,颈动脉窦IMT值与冠心病程度相关。结论:颈动脉窦IMT与冠心病程度明显相关,二者有共同的病理和血液动力学基础。颈动脉窦IMT可以用作监测冠状动脉粥样硬化的指标。
Objective To investigate the relationship between carotid atherosclerosis and coronary artery diseaseCAD and it's risk factors. Methods The intima-media thicknessIMT of 191 Patients with suspected CAD was evaluated for 16 sites of the carotid arteries common carotid internal carotid external carotid bifurcation near and far walls left and right sideswith ultrasonography. The subjects were stratified by coronary angiography. The atherosclerosis parameters were compared in these patients. Results Carotid and coronary arteries shared many risk factors such as aging and dyslipidemia. The IMT measurements of the CAD groups were significantly higher than those of the control group. Multivariate regression analysis revealed the significant association between bifurcation IMt and CAD extent. Conclusion IMT in the carotid bifurcation is related significantly with the extent of CAD. They share common pathological and hemodynamic basis. Carotid bifurcation IMT may be used as a marker for coronary atherosclerosis.
出处
《天津医药》
CAS
北大核心
2005年第3期148-150,共3页
Tianjin Medical Journal
