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Hepcidin与铁代谢及其在慢性肾性贫血方面的研究进展 被引量:1

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摘要 Hepcidin是新近发现的由肝脏分泌的小分子抗菌多肽 ,可以调节机体铁的吸收和储存以维持铁稳态。Hepcidin调节铁代谢的作用靶点为十二指肠肠细胞以及单核巨噬细胞。Hepcidin与慢性病性贫血的发生密切相关 ,在肾性贫血中起重要作用 。
作者 李静 樊均明
出处 《国外医学(泌尿系统分册)》 2005年第2期249-252,共4页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
关键词 贫血 肽类
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参考文献19

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同被引文献19

  • 1孙坚军.Hepcidin与炎症和贫血[J].医学综述,2005,11(3):216-218. 被引量:5
  • 2张怀,袁其朋,朱亚平,马润宇.人Hepcidin融合表达载体的构建及在大肠杆菌中的表达[J].中国生物工程杂志,2005,25(3):44-48. 被引量:7
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  • 6Vyoral D, Petr' ak J. Hepcidin: A direct link between iron metabolism and immunity.The International Journal of Biochemistry & Cell Biology, 2005, 37:1768-1773 被引量:1
  • 7Weinstein DA, Roy CN, Fleming MD et al. Inappropriate expression of hepcidin is associated with iron refractory anemia:implications for the anemia of chronic disease. Blood, 2002, 100(10):3776 - 3781 被引量:1
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  • 9Nicolas G, Chauvet C, Viatte L et al. The gene that codes for hepcidin, an iron regulatory hormone, is regulated by anemia,hypoxia, and inflammation. Clin Invest,2002, 110:1037- 1044 被引量:1
  • 10Yamaji S, Sharp P, Ramesh B et al. Inhibition of iron transport across human intestinal epithelial cells by hepcidin. Biood, 2004,104(7):2178 - 2180 被引量:1

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