摘要
应用银染技术,对24例结肠腺癌Ⅱ级不典型增生,30例绒毛状腺瘤,14例绒毛状腺瘤Ⅲ级不典型增生和29例高分化管状腺癌进行银染核仁形成区嗜银蛋白(Ag-NORs)定量研究,观察Ag-NORs数量、形态、大小和分布在结肠肿瘤交界性病变中的表达.提示Ag-NORs四项指标定量研究对结肠脉瘤,特别是Ⅲ级不典型增生与绒毛状腺瘤之结肠癌前病变有较好的监测作用.
The expression of argyrophil proteins associated with the nucleolar or-ganizer regions (Ag-NORs) in borderline colorectal lesions was studied. We examined 24 Ⅲ grade atypical hyperplasia of the adenomas, 30 villous adenomas, 14 Ⅲ grade atypical hyperplasia of the villous adenomas and 29 well-diffrentiated tubular adnocar-cinomas by this mtehod. The number, shape, size and distribution of Ag-NORs were counted and analysed. These results suggest that the four quantitative parameters of Ag-NORs were well evaluated in precarcinomatous lesion of the adenomas, particu-larly Ⅲ grade atypical hyperplasia and villous adenoma of the colon.
出处
《临床消化病杂志》
1994年第4期145-148,共4页
Chinese Journal of Clinical Gastroenterology
基金
中华医学基金
关键词
结肠肿瘤
癌前病变
核仁形成区
嗜银蛋白
Argyrophil proteins associated with nucleolor organizer regions (AgNORs) Colorectal tumor Hyperplasia Precancerous lesions
