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4种方法检测血浆载脂蛋白A-I结果的比较 被引量:2

COMPARISON OF FOUR METHODS IN MEASURING PLASMA APOLIPOPROTEIN A-Ⅰ LEVELS
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摘要 用脱脂RID、不脱脂RID、EIA、ITA 4种方法对60例正常人、79例非胰岛素依赖型糖尿病(NIDDM)患者和39例冠心病(CHD)患者同时进行了血浆脂蛋白(apo)A-Ⅰ水平的测定。结果显示,正常人中apoA-Ⅰ水平脱脂RID法与不脱脂RID、EIA、ITA有极密切相关,r值分别为0.8091、0.6430、0.6281;脱脂RID法所测正常人血浆apoA-Ⅰ水平为152.58±18.51 mg/dl,非常显著高于其它3种方法,且脱脂RID法所测apoA-Ⅰ水平在三组间有极显著差异。表明脱脂RID法检测血浆apoA-Ⅰ水平对诊断糖尿病心血管并发症、冠心病有特异性。 Plasma apoA- I of sixty normal subjects, seventy-nine NIDDM patients and thirty-nine coronary heart disease (CHD) patients were measured by delipidated RID, non-delipidated RID, EIA and ITA. The mean apoA- I level in controls(152. 58± 18. 51 mg/dl)by delipidated RID was much higher than that by non-delipidated RID,El A and ITA. The levels of apoA- I measured by four methods were closely related. Amount of apoA- I measured by delipidated RID was different fron those by ether three methods. The results showed: the plasma apoA- I level measured by delipidated RID was better in diabetics and CHD.
出处 《中日友好医院学报》 1993年第3期157-160,共4页 Journal of China-Japan Friendship Hospital
关键词 载脂蛋白A-Ⅰ 单向免疫扩散 检测 apolipoprotein A-I delipidation radial-immuno-diffusion electroimmunoassay immuno-turbidimetric-assay
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