摘要
观察了高速投射物所致狗颌面部重型火器伤后,远隔重要脏器心、肺早期损伤发生率及组织学和超微结构改变。43.9%(25/57)的动物发生远隔脏器损伤,其中肺脏、心脏损伤发生率分别为42.1%和31.6%,心、肺损伤的组织学特点表现为点、片状出血,超微结构改变肺脏表现为肺泡上皮细胞、毛细血管内皮细胞的损伤,心脏表现为心肌纤维的区域性损伤及细胞器的变性。这些损伤改变均会影响心、肺正常代谢及功能,处理不当会影响伤情的转归及预后,可能成为严重心、肺并发症发生、发展的病理基础。作者对损伤发生机理及相关临床意义进行了讨论。
This experiment was designed to study the incidence of the heart and lung injuries which were distant from the projectile wound of the maxillofacial regionsin dogs.43.9% of the animals(25/57)were found tohave injuries in their organs distant to the wound,withan incidence of heart injury being 31.9%,and lung in-jury 42.1%.The histopathological changes of theheart and lungs were characterized by pu(?)ctate andpatchy hemorrhage;the ultrastractural changes of thelungs included the injuries of type Ⅰ and type Ⅱpneumocytes and the capillary cndothelia;the changesof the heart under electron miccroscope were reginalinjury of the myocardial fibers and degeneration of theorganelles.All pathological changes could affect thenormal metabolism and functions of the heart and thelungs,which would affect the course and prognosis ofthe disease,and might be the basis of severe cardio-pulmonary complications in case of inappropriatetreatment.The pathogenesis and the clinical signifi-cance of the injury were also discssed.
出处
《中国危重病急救医学》
CAS
CSCD
1993年第3期133-135,共3页
Chinese Critical Care Medicine
关键词
颌面
创伤
心
肺
病理学
maxillofacial
trauma
heart
lung
pathology
