摘要
目的:观察三苯氧胺配伍阴道放置米索前列醇终止早孕的临床效果,探讨其可行性。方法:将停经≤50天自愿要求药物流产者随机分成两组,观察组40例,每日早晚空腹口服三苯氧胺20mg,连服4天,第5天上午阴道放置米索前列醇600μg;对照组40例,每日早晚空腹口服米非司酮25mg,连服3天,第4天上午口服米索前列醇600μg。结果:观察组完全流产率为92.5％,有效率为97.5％,效果确切。对照组完全流产率为95％,与观察组比较,无显著性差异(P>0.05)。观察组较对照组流产中及流产后出血量少,出血天数缩短,月经恢复快。结论:三苯氧胺配伍阴道放置米索前列醇终止早孕效果确切,且流产中及流产后出血量少,出血天数缩短,月经恢复快,值得在临床推广应用。
Objective: To observe clinical effect of tamoxifen combined with vaginal misoprostol on terminating early pregnan-cy. Methods: Abortion volunteers who had less than 50 amenorrheal days were divided into two groups randomly. 40 cases in observation group fasting took 20mg tamoxifen every morning and night for 4 days, and were placed 600μg misoprostol into va-gina in the morning of the fifth day. Result: Rate of complete abortion was 92. 5% , and rate of effectiveness was 97. 5% , and
result was remarkable in the observation group. Rate of com-plete abortion in control group was 95%. There was no signifi-cant difference, ( P > 0.05 ) between two groups. Comparing observation group with control group, the former shortened bleeding days and renewed emmenia quickly. Conclusion: There is definite effect on terminating early pregnancy using tamoxifen combined with vaginal misoprostol. It takes advantage of reducing bleeding, shorten bleeding time and renew emmenia quickly. It can be recommended in the clinic.
出处
《中国计划生育学杂志》
2003年第12期743-745,共3页
Chinese Journal of Family Planning
