摘要
目的 :探讨抗淋巴细胞球蛋白联合环孢素A治疗重型再生障碍性贫血 (SAA)的临床疗效及副作用。方法 :抗淋巴细胞球蛋白联合环孢素A、甲强龙、十一酸睾酮治疗SAA 1 1例 ,并与同期应用环孢素A(CsA)联合十一酸睾酮治疗 1 2例SAA进行对比 ,按全国统一疗效标准评价疗效。结果 :联合用药组有效率 81 .8% ,环孢素A及十一酸睾酮组有效率 5 0 .0 % ,抗淋巴细胞球蛋白联合甲强龙降低了血清病的发生 ,CsA的副作用较轻 ,不影响治疗。结论
Objective:To observe whether simultaneous administration of ALG and CsA could further improve response rates of SAA .Methods:11 cases of SAA were treated with ALG and CsA,12 cases were treated with CsA .Result:the response rate of ALG and CsA group (81.8%) was higher than that of CsA group (50.0%), steroids combined with ALG minimized serum sickness. the side effect of CsA was slight.Conclusion:A combination immunosuppressive regimen containing both ALG and CsA could improve response rates.
出处
《长治医学院学报》
2004年第4期255-256,共2页
Journal of Changzhi Medical College
基金
长治医学院科研发展基金支助项目 ( 0 2 0 2 )
