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新生儿细菌感染时血清IL-8和IL-13水平变化 被引量:9

Primary study on the dynamic changes of the IL-8 and IL-13 in newborn with various bacterial infections
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摘要 目的探讨血清IL-8和IL-13水平在新生儿细菌感染的早期诊断和临床转归中意义。方法用ELISA测定三组血清细胞因子的水平。感染组:21例细菌感染新生儿(治疗前和有效治疗后);非感染组:20例非感染性疾病新生儿;脐血组:30例正常新生儿。结果感染组IL-8和IL-13水平较非感染组升高(P<0.05);感染组治疗后IL-8水平较治疗前下降。结论新生儿细菌感染时血清IL-8和IL-13显著升高,可作为新生儿细菌感染的早期诊断指标,IL-8可用来评价疗效。
出处 《临床儿科杂志》 CAS CSCD 北大核心 2004年第9期598-600,共3页 Journal of Clinical Pediatrics
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