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急性冠脉综合征与心肌肌钙蛋白I相关性定量研究 被引量:3

Quantitative study of the correlation between acute coronary syndromes and cardiac troponin I
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摘要 目的:旨在明确急性冠脉综合征(ACS)患者冠状动脉狭窄程度及左室射血分数与血清心肌肌钙蛋白I (cTnI)峰值水平的相关性,并明确与预后的关系。方法:选择行经皮冠状动脉造影(CAG)的ACS患者51例,检测 其cTnI水平,并行超声心动图(UCG)检查,统计1月内主要心血管事件(MCE)发生情况。按CAG显示的冠状动 脉狭窄程度将患者分为3组。结果:三组患者cTnI峰值水平有统计学差异,即冠脉狭窄程度越重,其cTnI的峰值 越高;左室射血分数(LVEF)<40%患者的cTnI峰值较LVEF≥40%者明显升高;合并MCE的患者cTnI峰值明 显升高。结论:冠脉病变严重程度与cTnI峰值呈正相关、LVEF与cTnI峰值呈负相关,并有预后价值。 Objective: To find out a quantitative correlation, if any, between the severity of coronary artery disease, assessment of left ventricular function and peak cTnI. Methods: Fifty-one patients underwent acute coronary syndrome(ACS) were involved. According to the severity of coronary artery disease, we divided them into three groups. Peak cTnI level and ultrasound cardiogramwere needed in every patient. Major cardiovascular events were observed for a month. Results: The peak cTnI levels of the three groups were statistically different. The peak cTnI levels whose LVEF<40% were statistically higher than those whose LVEF≥40%. The peak cTnI levels with MCE were statistically higher than those without MCE. Conclusion: There was significant relationship between CAG results, LVEF levels and peak cTnI levels. Patients who had MCE had higher cTnI level. Thus, peak cTnI had diagnostic and prognostic value for ACS.
作者 刘芳 邢启崇
出处 《中国中西医结合影像学杂志》 2004年第4期261-262,271,共3页 Chinese Imaging Journal of Integrated Traditional and Western Medicine
关键词 cTnⅠ 患者 心肌肌钙蛋白Ⅰ 急性冠脉综合征 LVEF CAG 冠状动脉狭窄 ACS 左室射血分数 升高 The severity of coronary artery disease Assessment of left ventricular function Cardiac troponin I(cTnI) Acute coronary syndrome(ACS)
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