摘要
以对氯苯甲醛和丙酮为原料 ,以PSTEA作相转移催化剂合成对氯苄叉丙酮。对氯苄叉丙酮经磺化反应合成了苄叉丙酮磺酸钠。讨论了影响缩合反应与磺化反应的主要因素 ,得到了最佳反应条件。合成对氯苄叉丙酮的最佳工艺条件 :以 0 .4gPSTEA为催化剂 ,15ml5 %的NaOH为反应介质 ,0 .1mol对氯苯甲醛与 2 0ml丙酮缩合 ,对氯苄叉丙酮的收率达97% ;合成苄叉丙酮磺酸钠的最佳工艺条件 :以 0 .0 0 2mol氧化镁为催化剂 ,0 .1mol对氯苄叉丙酮与 0 .13mol亚硫酸钠在15 0℃反应 3h ,对氯苄叉丙酮的收转化率为 82 %。
P-chlorobenzalacetone is synthesized from p-chlorobenzaldehyde and acetone employing PSTEA as phase transfer catalyst. Sulphobenzalacetone sodium salt is synthesized through sulfonation reaction. The influence factors of condensation reaction and salfonation reaction are investigated and the optimum reaction conditions are achieved. The optimum technology conditions of p-chlorobenzalacetone are as follows: 0.4 g PSTEA used as catalyst; 15 ml 5%sodium hydroxide used as reaction medium; p-chlorobenzalacetone is synthesized through condensation reaction using 0.1 mol p-chlorobenzaldehyde and 20 ml acetone as the material; the yield of p-chlorobenzalacetone is about 97%. The optimum technology conditions of sulphobenzalacetone sodium salt are as follows: 0.002 mol magnesia used as catalyst; the reaction time is 3 h; the reaction temperature is 150 ℃; sulphobenzalacetone sodium salt is synthesized through sulfonation reaction using 0.1 mol p-chlorobenzalacetone and 0.13 mol sodium sulfiteas the material; the percent conversion of p-chlorobenzalacetone is about 82%.
出处
《东华理工学院学报》
2004年第3期268-270,共3页
Journal of East China Institute of Technology
