摘要
目的 :血清总胆固醇 (Tch)、甘油三酯 (TG)、高密度脂蛋白胆固醇 (HDL -C)、低密度脂蛋白胆固醇 (LDL -C) ,这些指标目前均认为与冠心病 (CHD)危险性具有相关性。但单一因素对冠心病的诊断并不满意。因此人们提出用血脂的综合指标 (致动脉硬化指数 )对CHD诊断更有意义 ,认为它们对冠心病诊断更为敏感。本文通过对 6 4例冠心病患者和 5 4例正常对照者进行了Tch、TG、HDL -C、LDL -C、LDH -C/HDL -C、Tch/HDL -C和Tch -HDL -C/HDL -C的测定和计算 ,为CHD的诊断提供更有效的生化指标。方法 :Tch、TG、HDL -C、LDL -C测定在全自动生化分析仪进行。结果 :6 4例冠心病组血脂测定与 5 4例正常对照组比较 ,冠心病组HDL -C和LDL -C指标与对照组差别有显著性 (P <0 .0 5 )。血脂综合指数Tch/HDL -C、LDL -C/HDL -C和Tch -HDL/HDL -C冠心病组与正常对照者差别均有高度显著性 (P <0 .0 5 )。结论
Objective:To study the significance of composite index of the serum lipid variables in predicting coronary heart disease. Methods: A total of 118 people entered the study. They were divided into two groups: ①CHD; ②normal. The serum concentration of Cholesterol (Tch), Triglycerides (TG), High density lipoprotein cholesterol (HDL-C), Low density lipoprotein cholestero l(LDL-C) were determined. Tch/HDL-C, LDL-C/HDL-C and Tch-HDL/HDL-C were calculated. Results: The serum concentration of HDL-C in CHD was decreased compared with those in normal.(1.21±0.33 vs.1.59±0.43,P<0.05). The serum concentration of LDL-C in CHD was significant increased compared with those in normal.(12.47±0.70 vs. 1.99±0.64,P<0.05). Tch/HDL-C, LDL-C/HDL-C and Tch-HDL/HDL-C in CHD were significant higher than those in normal.(5.29±2.93 vs.2.96±0.79;2.20±0.86 vs.1.33±0.49;2.94±1.17 vs.1.96±0.79 P<0.01).In conclusion,the significance of compositeindex of the serum lipid variables are much important factors than single index of the serum lipid variables.
出处
《青海医药杂志》
2004年第9期16-17,共2页
Qinghai Medical Journal
