摘要
目的:分析肿瘤部位、等级、患者年龄以及是否接受过正规化疗4个因素对胶质瘤患者生存时间的影响。方法:收集80例胶质瘤术后患者临床资料,构建Cox回归模型,用Kapmeier-Meier法计算生存率并绘制生存曲线,运用Log-rank法和Cox回归模型进行单因素和多因素的生存分析。结果:肿瘤等级(RR=2.78)和是否接受过正规化疗(RR=0.25)是影响胶质瘤患者预后的独立的危险因素。结论:胶质瘤的恶性等级是决定其预后的主要因素,对胶质瘤患者进行正规化疗能有效延长患者生存时间。
AIM:To investigate the effects of tumor site,grade,patients age and regular chemotherapy on the survival time of the patients with glioma. METHODS:The data of 80 patients operated for glioma were collected so as to establish Cox regressive model.Survival rates were counted and survival curves were drawn with Kapmeier Meier methods.Single and multiple factors for survival were analyzed with Log rank method and Cox regressive model. RESULTS:Tumor grade(RR=2.78) and regular chemotherapy(RR=0.25) were the independent risk factors for the prognosis of patients with glioma. CONCLUSION:Glioma grade is the major prognostic factor,but the patients who accept the regular chemotherapy can extend their life spans significantly.
出处
《中国临床康复》
CSCD
2004年第32期7098-7099,共2页
Chinese Journal of Clinical Rehabilitation
