摘要
[目的 ]了解年龄和性别因素对人群的血清脂肪酸水平的影响。 [方法 ] 14 0名非高脂血症者 ,按照年龄分为 2 0岁～组、41岁～组及 >61岁组 ,以气相色谱法测定其血清豆蔻酸 (C 14 :0 ) ;棕榈酸 (C16:0 ) ;油酸 (C18:1) ;亚油酸(C18:2 )和花生四烯酸 (C2 0 :4)含量。 [结果 ]① 41岁～组人群的血清棕榈酸 (C16:0 )和亚油酸 (C18:2 )含量均显著高于2 0～岁组和 >61岁组 ,并且其血清油酸 (C18:1)含量高于 2 0～岁组。 2 0～岁组的血清花生四烯酸 (C2 0 :4)显著高于 >61岁组。②按照性别分层分析 ,年龄组之间存在的差异与全样本人群组的差异情况基本相同。③同年龄组内 ,血清脂肪酸含量没有显著的性别差异。 [结论 ]血清棕榈酸 (C16:0 )、油酸 (C18:1)、亚油酸 (C18:2 )、和花生四烯酸 (C2 0 :4)含量在非高脂血症人群中存在着年龄组间差异 ,41岁～组的血清棕榈酸 (C16:0 )和亚油酸 (C18:2 )含量均显著高于 2 0岁～组和 41岁～组 ,并且其血清油酸 (C18:1)含量高于 2 0岁～组。 2 0岁～组的血清花生四烯酸 (C2 0 :4)显著高于 >61岁组。
To observe the relation of fatty acid composition of human serum lipids to age and sex. Serum was obtained from 140 screened normal adults divided into three groups according to their age, and measured with GC on myristic acid(C14:0),palmitic acid(C16:0),oleic acid(C18:1),linoleic acid(C18:2),arachidonic acid(C20:4). 1)Serum palmitic acid(C16:0) and linoleic acid(C18:2) levels were significantly higher for middle-aged persons than for the young and the old ones. Serum palmitic acid(C16:0) of the midlle-aged was significantly higher than that of the young, and arachidonic acid(C20:4)of the young was significantly higher than that of the old.2) The difference of three age groups stratified by sex was almost the same as that in the total.3) No significant difference was found between male and female in same age groups. [Conclusion] There was significant difference between ages for palmitic acid(C16:0),oleic acid(C18:1),linoleic acid(C18:2),arachidonic acid(C20:4) in normal adults.Serum palmitic acid(C16:0) and linoleic acid(C18:2) levels were significantly higher for middle-aged persons than for the young and the old ones. Serum palmitic acid(C16:0) of the midlle-aged was significantly higher than the young,and arachidonic acid(C20:4)of the young was significantly higher than the old.No significant difference between female and male was found for any serum fatty acid.
出处
《环境与职业医学》
CAS
北大核心
2004年第5期394-396,共3页
Journal of Environmental and Occupational Medicine
