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超声对颈动脉内膜中层厚度与动脉顺应性关系的研究 被引量:10

Ultrasonographic research on intima-media thickness of common carotid artery and vascular compliance
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摘要 目的探讨颈动脉内膜中层厚度(IMT)与动脉顺应性之间的关系。方法分别选取正常对照组40例,高血压无斑块组47例和斑块组31例,使用超声多普勒测量颈动脉IMT和血管内径的变化。动脉测试仪同步记录血压和动脉顺应性[大动脉弹性(C1),小动脉弹性(C2)]。结果内径、IMT在斑块组与无斑块组和对照组间有统计学差异(P<0.01),而后两组间无差异(P>0.05);C1,C2在三组之间差异均有显著性(P< 0.05)。在无斑块组,C2与IMT呈负相关(r = -0.387),而C1与IMT无相关性。在斑块组,C1,C2均与IMT呈负相关(r分别为-0.479 、-0.475)。结论颈动脉IMT与动脉顺应性间存在线性关系,联合应用可作为早期评价动脉粥样硬化的指标。 Objective: To investigate the relationship between intima-media thickness of the common carotid artery and vascular compliance. Methods: 120 subjects were divided into three groups, 40 normotensive individuals as the control group, 47 subjects in non-carotid artery plaque group, and 33 patients in carotid artery plaque group, IMT and diameter of CCA were measured using HP-5500 ultrasound with a high-resolution probe, blood pressure and artery compliance (C1-large artery, C2-small artery) were detected by using HDI DO-2020. Results: IMT and diameter of the CCA of carotid artery plaque group was markedly increased, compared with control group and non-carotid artery plaque group (P <0.01), but there was no statistical difference between control and non-carotid artery plaque groups (P >0.05). Both C1 and C2 among three groups were significantly different (P <0.05). C2 was negatively associated with IMT of CCA and there was no correlation between C1 and IMT of non-carotid artery plaque group. Both C1 and C2 were negatively associated with IMT in carotid artery plaque group. Conclusions: The linear relation is existed between IMT of CCA and vascular compliance, it should be indicators in the diagnosis of early atherosclerosis by combined using.
出处 《中国现代医学杂志》 CAS CSCD 2004年第20期114-116,共3页 China Journal of Modern Medicine
关键词 超声 颈动脉 弹性 内中膜 ultrasound carotid artery elasticity intima-media thickness
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  • 1张维忠.动脉弹性功能临床研究的现状和意义[J].中华心血管病杂志,2003,31(4):243-244. 被引量:84
  • 2[2]Cohn JN. Vascular compliance and cardiovascular implications.Heart Dis, 2002, 2(1): 52-56. 被引量:1
  • 3[3]Finkelstein SM, Collins VR, Cohn JN. Arterial vascular compliance response to vasodilators by Fourier and pulse contour analysis[J]. Hypertension, 1998, 12(2): 380-387. 被引量:1
  • 4[4]O'leary DH, Polak JF, Kronmal RA, et al. Carotid artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults [J]. N Engl J Med, 1993, 340 (1):14-22. 被引量:1

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