摘要
目的 探讨粥样硬化性肾动脉狭窄与冠心病、肾功能之间的关系。方法 2 5 4例患者冠脉造影的同时行肾动脉造影。结果 合并肾动脉狭窄的冠心病者较单纯冠心病患者冠脉多支病变 (5 8%∶2 7% ,P <0 .0 5 )及临床表现急性冠脉综合征者多 (86%vs72 % ,P <0 .0 5 ) ;肾动脉狭窄组中轻度血肌酐升高者增多 (3 3 %vs 11% ,P <0 .0 5 ) ,60 %的单侧肾动脉狭窄者狭窄侧肾脏缩小 ,肾动脉狭窄程度与分肾肾小球滤过率之间无相关性 (r =-0 .2 0 8,P >0 .0 5 )。结论 粥样硬化性肾动脉狭窄与冠心病、冠脉病变严重程度密切相关。血肌酐轻度升高可能是肾动脉狭窄的独立预测因素。
Objective To investigate the correlation between atherosclerotic renal artery stenosis, coronary artery disease and renal function. Methods Two hundred and fifty-four patients with CAD or suspected CAD were carried out renal artery angiography after coronary angiography. Results Among the patients with CAD, patients with ARAS tended to have 3-vessel CAD and acute coronary syndrome(58% vs 27%, 86% vs 72%, P<0.05); Patients with mildly increasing level of serum creatinine were more in ARAS group than in control group (33% vs 11%, P<0.05). 60% patients with unilateral ARAS had asymmetric renal size. The lack of relationship between the degree of renal artery stenosis and GFR of individual kidney(r=-0.208, P>0.05) was observed.Conclusion ARAS was associated with CAD and the severity of CAD. Mildly elevated creatinine concentration may be an independent predictor of ARAS.
基金
卫生部部属医院临床学科重点项目 (2 0 0 1 0 91 3)
