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通脉煎对大鼠脑缺血再灌注损伤的保护作用 被引量:1

The Protective Function of "Meridian-Unobstructing Decoction" to Injury Caused by Reperfusion in Cerebral Ischemia in Rats
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摘要 利用动物实验对临床上治疗缺血性脑血管病取得满意效果的通脉煎进行研究,观察脑缺血再灌注模型SD大鼠的正中神经诱发电位(SEP)的恢复情况,用TTC染色法观察脑组织梗死面积.利用密度梯度法和组织学方法观察脑皮质水肿情况及观察造模前14天.给两个不同剂量的通脉煎灌胃为预防组对它们的影响.以探讨通脉煎治疗缺血性脑血管病的作用机理。 Animal experiment was used to study 'Meridian-Unobstructing Decoction' already proved by satisfactory therapeutic effect in the treatment of ischemic cerebrovascular diseases for observation of rehabilitating situation of the evoked potential(SEP)of the median nerve in SD rat model with reperfusion after cerebral ischemia, for observation of the space in the cerebral infarction by TTC staining method, for observation of edema situation of cerebral cortex by the density gradient method and histological method and for observation of the influence to them by stomach feeding with two different dosages of ' Meridian-Unobstructing Decoction'as the prevention group, 14 days before the model was made, to investigate the functional mechanism of' Meridian Unobstructing Decoction' in the treatment of ischemic cerebrovascular disease.
出处 《上海中医药大学学报》 CAS 1999年第4期50-53,共4页 Academic Journal of Shanghai University of Traditional Chinese Medicine
基金 上海市卫生局基金!057
关键词 治疗 观察 脑缺血再灌注损伤 保护作用 脑皮质 不同剂量 缺血性脑血管 情况 效果 模型 Meridian-Unobstructing Decoction' cerebral ischemia evoked potential cerebral infarction
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