摘要
目的 :评价牙周袋内局部使用盐酸米诺环素软膏 ,辅助治疗逆行性牙髓炎的临床效果。方法 :选择逆行性牙髓炎 3 2例 ,随机分为实验组和对照组 ,均无原发牙体牙髓病。患牙有深达根尖区的牙周袋 (探诊深度≥ 5mm)。实验组 76个牙位点 ,对照组 84个牙位点。两组均同时进行牙髓治疗和牙周治疗。在龈上洁治和龈下刮治术后 ,实验组牙周袋内注入盐酸米诺环素软膏 ,对照组牙周袋内只用生理盐水冲洗 ,每周 1次 ,共 3次。在基线、治疗后第 4周、第 8周时 ,记录菌斑指数 (PLI)、探诊出血 (BOP)、牙周袋深度 (PD)、临床附着丧失 (CAL)等指标。结果 :治疗后第 4周和第 8周 ,两组各项指标测定值与基线相比均有明显改善 ,两次复查时实验组各指标的改善均明显优于对照组 ,差异有显著性 (P <0 .0 1)。结论 :牙周袋局部应用盐酸米诺环素软膏辅助治疗逆行性牙髓炎 ,能够获得较好的临床效果。
Objective:To evaluate the clinical effects of minocycline ointment (Perioline) supplementary treatment on retrograde pulpitis.Method: 32 patients with severe adult periodontitis (probing depth≥ 5mm) and with retrograde pulpitis were enrolled in the study. Following supragingival scaling and subgingival scaling the patients were randomized into test group (76 sites) and control group (84 sites). The endodontal and periodontal treatments were administered at each appointment. The periodontal pockets were administered either minocycline ointment in test group or saline solution in control group at baseline, week 2, and week 3. Clinical measurements, including plaque index (PLI), bleeding on probing (BOP), probing depth (PD) and clinical attachment loss (CAL), were analyzed at baseline, week 4 and week 8.Result: Both therapies resulted in significant improvements from baseline in PLI, BOP, PD and CLA scores. The improvements in clinical parameters were greater in test group than in control group. Conclusion: Subgingival administration of minocycline ointment (Perioline)in the treatment of retrograde pulpitis with periodontitis is safe and leads to significant clinical improvement after supragingival and subgingival instrumentation.
出处
《临床口腔医学杂志》
2004年第9期549-551,共3页
Journal of Clinical Stomatology
关键词
盐酸米诺环素
牙周炎
逆行性牙髓炎
牙周袋
minocycline
periodontitis
retrograde pupititis
periodontal pocket
