摘要
综述了聚合物胶束的自组装原理和结构、制备方法、体内过程和应用等。与传统的表面活性剂胶束比较,聚合物胶束具有良好的生物相容性和稳定性、较长的体循环时间,尤其在经过表面修饰后,还可有靶向和定位传递作用。
The self-assemble principle and structure of polymeric micelles are reviewed as well as their preparation,in vivo process and applications. Compared with the conventional surfactant micelles, the polymeric micelles possess goodbiocompatibility, stability and prolonged circulation time. After surface modification, they may have targeting and specificsite delivery effect.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2004年第10期626-630,共5页
Chinese Journal of Pharmaceuticals
关键词
聚合物胶束
自组装
药物传递
polymeric micelle
self-assemble
drug delivery
