摘要
采用微波常压合成法,控制温度条件下,快速制备了(+)N苄基氯化辛可宁,将其用于拆分1,1′联2萘酚外消旋体(BINOL),得R(+)BINOL收率60%,S(-)BINOL收率70%,效果良好。
The mixture of benzyl chloride and cinchonine was heated at 100～104℃in DMF for about 15min under microwave irradiation to give(+) N benzylcinchoninium chloride in 55 1% yield,the efficient resolution of racemic BINOL has been achieved with (+) N benzylcinchoninium chloride.
出处
《化学试剂》
CAS
CSCD
北大核心
2004年第4期241-242,共2页
Chemical Reagents
