摘要
目的 :探讨老年高血压患者血清肿瘤坏死因子 (TNF -α)、白细胞介素 - 6 (IL - 6 )的变化及其临床意义。方法 :采用放射免疫分析分别测定 1 6 5例老年高血压患者、5 0例老年健康体检者血清TNF -α、IL - 6的含量。结果 :老年高血压患者血清TNF -α、IL - 6含量明显高于对照组 ;血压未控制组血清TNF -α、IL - 6含量明显高于血压控制组。结论 :血清TNF -α、IL - 6的异常升高是老年高血压发病的病理因素之一 ;高水平的TNF-α、IL -
Objective To explore the clinical signifcance of changes of serum TNF-α and IL-6 levels in senile patients with hypertension. Methods Serum TNF-α and IL-6 levels were determined with RIA in 165 senile hypertensive patients and 50 controls. Results In senilc hypentensive patients, the serum TNF-α and IL-6 levels were significantly higher than those in the controls. The patients with uncontrolled hypertension ( n=88 ) had higher serum TNF-α and IL-6 levels than those in the well-controlled patients ( n=77 ). Conclusion Abrormal high serum TNF-α and IL-6 levels were one of the main pathophysiologic features in senile hypertension and might contribute to the intractability.
出处
《放射免疫学杂志》
CAS
2004年第4期270-271,共2页
Journal of Radioimmanology
