期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

细菌耐药性产生的分子机制与耐药基因的快速检测方法 被引量：5

Molecular mechanism of bacterial resistance to antibiotics and rapid methods for detecting antimicrobial resistant gene
下载PDF
导出
摘要 　细菌产生耐药性成为临床治疗感染性疾病失败的主要原因。本文综述了由自发基因突变和获得性细菌耐药性产生的分子机制,及目前常用的快速检测细菌耐药基因的方法,包括聚合酶链反应-单链构象多态性分析(PCR SSCP)、质粒指纹图谱分析和PCR 限制性片段长度多肽性分析(PCR RFLP)。 It is considered that the bacterial resistance to antibiotics is one of the major causes of failure to (controlling) infectious (diseases). In this paper, the current situation and mechanism of bacterial resistance to (antibiotics) and a series of methods for detecting antimicrobial resistant gene were described.
作者 崔晓文 张秀英
机构地区 东北农业大学动物医学院
出处 《中国兽药杂志》 2004年第9期30-32,共3页 Chinese Journal of Veterinary Drug
关键词 细菌 耐药性 分子机制 基因 检测方法 bacterial resistance molecular mechanism gene detecting method
分类号 S852.61 [农业科学—基础兽医学] S859.7 [农业科学—兽医学]
  • 相关文献

参考文献11

  • 1Martine-Freijo P, Fluit AC, Schmitz FJ, et al. Class 1 integrons in Gram-negative isolates from different European hospitals and association with decreased susceptibility to multiple-antibitic compounds[J]. J Amtimicrob Chemother, 1998, 42: 689. 被引量：1
  • 2Bass L, Liebert CA, Lee MD, et al. Incidence and characterization of integrons, genetic elements mediating multiple-drug resistance in avian Escherichia coli [ J ]. Antimicrobial Agents and Chemotherapy, 1999, 43 (12): 2925 - 2929. 被引量：1
  • 3Bunny KL, Hall RM, Stokes HW. New mobile gene cassettes containing an aminoglycoside resistance gene, aacA7, and a chloramphenicol resistance gene, catB3, in an integron in pbwh301 [J].Antimicrobial Agents and Chemotherapy, 1995, 3:686 -693. 被引量：1
  • 4McDonalc LC, Kuehnert MJ, Tenove FC. Vancomycin-resistant enterococci outside the health-care setting: prevalence, sources,and public health implications [ J ]. Emerg Infect Dis, 1997, 3:311 -317. 被引量：1
  • 5Levesque C, Piche L, Larose C, et al. PCR mapping of integrons reveals several novel combinations of resistance genes [ J ]. Antimicrob Agents Chemother, 1995,39( 1 ): 185 - 191. 被引量：1
  • 6Davies J, Smith DI. Plasmid-determined resistance to antimicrobial agents[J]. Annd Rev Microbiol, 1978, 32:469 -518. 被引量：1
  • 7Dorthe S, Frank MA, Lars BJ. Characterisation of integrons and antibiotic resistance genes in Danish multiresistants Salmonella entericaTyphimurium DT104 [J]. FEMS Microbiology Letters,1998, 160:37-41. 被引量：1
  • 8Mobak KDL, Baggesen FK, Aarestrup JM, et al. An outbreak of multidrug-resistant, quinolone-resistant Salmonella enterica serotype Typhimurium DT104 [ N ]. Engl Med, 1999, 341: 1420-1425. 被引量：1
  • 9Corpet DE, Lumeau S, Corpet F. Mimimum antibiotic levels for selecting a resistance plasmid in a gnotobiotec animal model [ J ].Antimicrobial Agents and Chemotherapy, 1989, 33 (4): 535-540. 被引量：1
  • 10Tribble GD, Parker AC, Smith CJ. Genetic structure and transcriptional analysis of a mobilizable, antibiotic resistance transposon from bacteroides[J]. Plasmid, 1999, 42( 1 ): 1 - 12. 被引量：1

同被引文献63

引证文献5

二级引证文献29

中国兽药杂志
2004年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部