摘要
用ＳｏｕｎｄＳｃａｎ２０００骨定量超声（ＱＵＳ）仪测量胫骨超声速度（ＳＯＳ），同时与单光子吸收法（ＳＰＡ）测量前臂１／３处骨矿密度（ＢＭＤ）比较。两方法测得２０８例患者和健康志愿者结果相关（ｒ＝０．６７８，Ｐ＜０．００１）。４２例健康绝经妇女ＳＯＳ和ＢＭＤ与绝经时间呈负相关（ｒ＝－０．４１７和－０．４７９，Ｐ＜０．０１），７３例＞４０岁的健康志愿者ＳＯＳ和ＢＭＤ与年龄呈负相关（ｒ＝－０．２９３和－０．３７３，Ｐ＜０．０５）。与性别和年龄相匹配的正常参考值比较，结果＜ｘ－２ｓ者ＱＵＳ检出３４例，占１６．３％；ＳＰＡ２３例，占１１．０％，ＱＵＳ的诊断敏感度约是ＳＰＡ的１．５倍。
We have assessed a new method of quantitative ultrasound (QUS,with SoundScan 2000 of Myriad Ultrasound Systems Ltd)for measuring the speed of sound(SOS,m s-1) and diagnosis of osteoporosis in the conical bone of the right tibial shaft. The QUS was compared with single photon absorptiometry(SPA) for measuring the bone mineral density (BMD, g cm-2) at the forearm (1/3 site).SOS significantly correlated with BMD (r= 0. 678, P<0. 001 ) in 208 subjects, including patients with various metabolic bone diseases and 99 healthy volunteers by QUS and SPA. The QUS was most reproducible with intra- and intercoefficients of 0. 22% and 0. 39% respectively. In the healthy late postmenopausal women,there was a correlation of SOS and BMD with years since menopause (r =-0. 417 and -0. 479,P<0. 01 and 0. 002). In the healthy volunteers aged over 40 years,there was also a correlation of SOS and BMD with age(r=-0. 293 and -0. 373,P<0. 05 and 0. 01 ). Compared with healthy subjects matched by sex and age,34 cases by QUS and 23 cases by SPA were were detected to have the values lower than x-2S of healthy subjects,the diagnostic sensitivity of QUS to SPA being about 1. 5 times. The results show that the technique of QUS is highly sensitive and precise. The diagnosis of osteoporosis and prediction of osteoporotic fracture by QUS are satisfactory.
出处
《中国骨质疏松杂志》
CAS
CSCD
1997年第1期43-45,共3页
Chinese Journal of Osteoporosis
