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大鼠听皮层神经元频率感受野的可塑性 被引量:3

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摘要 应用常规电生理学技术,以神经元的最佳频率、频率一反应曲线和频率调谐曲线为指标,研究神经元频率感受野可塑性.结果表明,在给予的条件刺激频率和神经元最佳频率相差1-4kHz范围内,条件刺激均可引起神经元频率感受野转移,但频率相差越小,感受野转移概率越高.感受野可塑性与条件刺激诱导的时程有关,条件刺激和神经元最佳频率相差越大,所需条件刺激的诱导时间越长.条件刺激撤除后感受野的复原则呈现相反的趋势.条件刺激频率高于或低于神经元的最佳频率均可能引起感受野变化,可塑性变化不具有明显方向性.但有的神经元感受野变化呈现双侧性,有的神经元只有单侧性变化.结果显示,神经元频率感受野可塑性是研究可塑性机制的理想模型,为深入研究听觉模态的学习记忆神经机制提供了重要实验资料。
出处 《科学通报》 EI CAS CSCD 北大核心 2004年第11期1062-1067,共6页 Chinese Science Bulletin
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参考文献17

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同被引文献49

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