摘要
目的:分析立体适形放射治疗(3D-CRT)前列腺癌的疗效。方法:采用3D-CRT治疗前列腺癌29例,26例放疗前行双侧睾丸切除,22例同时服用内分泌治疗药物。采用3D-CRT技术,5次/周,1.8～2Gy/次,DT60～72Gy,中位剂量68Gy。结果:中位随访18个月,生存率82.8%,肿瘤特异生存率93.1%。1、2、3级急性胃肠道不良反应发生率分别为44.8%,6.9%,3.4%,1、2级急性泌尿生殖系统不良反应发生率分别为34.5%,6.9%。结论:3D-CRT治疗前列腺癌疗效满意,不良反应小。
Objective: To evaluate the outcome of prostate carcinoma treated with three-dimensional conformal radiotherapy(3D-CRT). Methods: To retrospectively analyze 29 patients with prostate carcinoma treated with 3D-CRT. The patients of twenty-six cases underwent orthiectomy before radiation therapy and that of 22 cases received orchiectomy combined with hormone treatment. All patients received 3D-CRT with a median dose of 68Gy, 1.8-2.0Gy per fraction, five fractions weekly. Results: The median follow-up duration was 18 months. The overall survival was 82.8% and the disease specific survival was 93.1%. In terms of acute GI side effects, the frequencies of Grade Ⅰ,Ⅱor Ⅲ reactions were 44.8%, 6.9%, 3.4%, while GradeⅠor Ⅱ acute GU side effects were 34.5%, 6.9%, respectively. Conclusion: The outcome of 3D-CRT for patients with prostate carcinoma is satisfactory, and the side effects tolerable to most patients.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2004年第14期814-816,共3页
Chinese Journal of Clinical Oncology
关键词
肿瘤
前列腺肿瘤
放射治疗
立体适形放射治疗
Tumor Prostate carcinoma Radiotherapy Three-dimensional conformal radiotherapy (3 D-CRT)
