摘要
本文应用立体计量方法,对20例骨母细胞型骨肉瘤进行回顾性研究,旨在为组织学分级提供客观的形态计量依据。标本常规固定、包埋、切片及HE染色,按公式计量瘤细胞核体积均值((?)v);(?)v=π/3Lo^3,其中Lo为沿测试线方向测试点所落细胞核间距的长度。结果表明骨母细胞骨肉瘤(?)v值在85～765μm^3范围,且与Price分级和肿瘤预后相关,应用这种方法测量核体积为估价骨母细胞型骨肉瘤预后提供了客观依据。
Twenty cases of osteoblastic sarcoma were studied retrospectively with the stereometric method in order to provide objective morphometric data for the histological grading of the tumor.After standard fixation,embedding,sectioning and hematoxylin eosin staining,the average nuclear volume Vv was determined with the formula as follows;In the formula,Lo stands for the distance between 2 points resulting from the interception of a testing line through a nucleus.It was found that the Vv of osteoblastic sarcoma varied from 85 to 765μm3 and was consistent to the prognosis predicted with the Price's grading of sarcoma.It is believed that the determination of the stereomtric nuclear volume of osteoblastic sarcoma is able to provide an objective criterion for the prognosis of the tumor.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1993年第4期325-328,共4页
Journal of Third Military Medical University
关键词
骨母细胞
立体计量学
成骨肉瘤
osteoblasts sarcoma
stereometry
nuclear volume
