摘要
目的比较18F-脱氧葡萄糖(FDG)PET/CT与磁共振成像(MRI)对肺癌脊椎转移临床诊断价值的差异。方法 35例肺癌患者同时行18F-FDG PET/CT及MRI检查,比较两种方法诊断脊椎转移病灶的敏感性和特异性。统计学方法采用配对四格表资料c2检验,P<0.05被认为差异有统计学意义。结果经病理或随访确诊脊椎转移患者27例。以受累椎体病灶个数为统计单位,脊椎范围内共875个椎体,158个为真阳性,717个为真阴性。PET/CT诊断正确148个病灶,假阴性10个,假阳性24个,其敏感性93.6﹪,特异性96.8﹪。MRI诊断正确150个病灶,假阴性8个,无假阳性,其敏感性94.9﹪,特异性100﹪。结论对肺癌脊椎骨转移的诊断,MRI较PET/CT具有更高的敏感性、特异性。
Objective To compare the ability of 18F-FDG PET/CT and MRI in the detection of centrum metastasis of lung cancer. Methods 35 patients with lung cancer were imaged with both 18F-FDG PET/CT and MRI. All the cases were proved by histopathology. The author compared the demonstration of centrum metastases with the two imaging modalities. Statistical analysis was performed using the 2×2 contingency table c2 test. A P value of less than 0.05 was considered to indicate statistical significance. Results In the centrum region, 27 of 35 patients with lung cancer were proved to have centrum metastases. Taking the total lesions as the samples, 158 lesions in 875 centrums were demonstrated as metastatic lesions. In 18F-FDG PET/CT, true positive lesions were 148, false negative lesions were 10, false positive lesions were 24, the diagnostic sensitivity was 93.6﹪, the diagnostic specificity was 96.8﹪. In MR imaging, true positive lesions were 150, false negative lesions were 8, false positive lesions were 0, the diagnostic sensitivity was 94.9﹪, the diagnostic specificity was 100﹪. Conclusion In the detection of centrum metastasis, MRI has a higher diagnostic sensitivity and specificity than 18F-FDG PET/CT.
出处
《功能与分子医学影像学（电子版）》
2012年第3期191-194,共4页
Functional and Molecular Medical Imaging(Electronic Edition)
关键词
肺癌
脊柱
肿瘤转移
磁共振成像
X线计算机
正电子发射断层显像
lung cancer
spine
neoplasm metastasis
magnetic resonance imaging
tomography X-ray computed
positron emission tomography
