DESIGN，SYNTHESIS　AND　ACTIVITIES　OF　ANALOGS　AND　SEGMENTS　OF　THE　PAPAVER　SOMNIFERUM　POLLEN　PEPTIDE　PSPP2~1

DESIGN,SYNTHESIS AND ACTIVITIES OF ANALOGS AND SEGMENTS OF THE PAPAVER SOMNIFERUM POLLEN PEPTIDE PSPP2￣1

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摘要 Four analogs and three segments of the Papaver somniferum pollen peptide 2 (PSPP2)were desiged and synthesized by using Merrifield solid phase peptide synthesis method. Their antitumour activities were detrminde by the tetrazolium salt MTT (3-(4,5-dimethylthiazol-2-yl)-2,5diphenyl tetraolium bromide) method and the relationship of tructure -activity was discussed. Four analogs and three segments of the Papaver somniferum pollen peptide 2 (PSPP2)were desiged and synthesized by using Merrifield solid phase peptide synthesis method. Their antitumour activities were detrminde by the tetrazolium salt MTT (3-(4,5-dimethylthiazol-2-yl)-2,5diphenyl tetraolium bromide) method and the relationship of tructure -activity was discussed.

作者 Jia Xi XU Sheng JIN (School of Chemistry and Molecular Engineering, Peking University, Beijing 100871)(National Laboratory of Applied Organic Chemistry at Lanzhou University, Lanzhou 730000)Meng Shen CAI (School of Pharmaceutical Sciences, Beijing Medical

出处《Chinese Chemical Letters》 SCIE CAS CSCD 1995年第11期941-942,共2页 中国化学快报（英文版）

关键词 PSPP2~1 PEPTIDE POLLEN SOMNIFERUM ANALOGS ACTIVITIES

分类号 O636 [理学—高分子化学]

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Chinese Chemical Letters

1995年第11期

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DESIGN，SYNTHESIS　AND　ACTIVITIES　OF　ANALOGS　AND　SEGMENTS　OF　THE　PAPAVER　SOMNIFERUM　POLLEN　PEPTIDE　PSPP2~1

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DESIGN，SYNTHESIS AND ACTIVITIES OF ANALOGS AND SEGMENTS OF THE PAPAVER SOMNIFERUM POLLEN PEPTIDE PSPP2~1

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DESIGN，SYNTHESIS　AND　ACTIVITIES　OF　ANALOGS　AND　SEGMENTS　OF　THE　PAPAVER　SOMNIFERUM　POLLEN　PEPTIDE　PSPP2~1