摘要
目的 研究不稳定型心绞痛患者发作/缓解期血清超敏C -反应蛋白(hs- CRP)水平的动态变化。 方法 对29例不稳定型心绞痛患者发作前后连续监测hs- CRP动态变化,hs- CRP测定方法为增效胶乳散射速率免疫比浊法,同时用化学发光法检测血清肌钙蛋白(cTnI)含量,并与30 例正常对照组进行比较。 结果 不稳定型心绞痛患者发作/缓解期血清hs- CRP均高于正常对照组(P<0 .01),并于发作前2日内出现血清hs- CRP含量升高,发作当日hs- CRP水平达到高峰,与缓解期相比均有高度显著性差别(P<0 .01),hs -CRP与cTnI变化成正相关。 结论 不稳定型心绞痛患者血清hs- CRP的连续监测对预测心绞痛发作具有一定价值。
Objective To study the serial changes of serum hypersensitive C-reactive protein level in unstable angina patients. Methods Serial serum hs-CRP levels were detected by the enhanced immunoturbidimetric assay in 29 unstable angina patients during onset/remission stage. cTnI was also detected by chemiluminescence immunoassay. Results Serum hs-CRP and cTnI levels in unstable angina patients were higher than those in normal control. hs-CRP level increased within 2 days before the angina onset, and reached the peak at the very day of onset. Serum hs-CRP and cTnI were positively correlated. Conclusion Serial detection of serum hs-CRP in unstable angina patients may help forecast the onset of unstable angina.
出处
《总装备部医学学报》
2005年第1期12-14,共3页
Medical Journal of General Equipment Headquarters
