摘要
目的:观察艾灸督脉对恶性肿瘤患者化疗后血液指标的影响。方法:90例恶性肿瘤患者化疗后白细胞下降者属脾肾两虚证型者分为两组,每组45例。治疗组艾灸督脉背部穴位配合皮下注射G-CSF每日100μg,对照组皮下注射G-CSF每日100μg,并观察两组患者治疗前后患者的血液指标变化情况。结果:治疗5天对照组白细胞上升至超出正常范围,且高于治疗组,差异有统计学意义(P<0.05),治疗组血小板水平较对照组升高,差异有统计学意义(P<0.05);治疗10天对照组白细胞下降,治疗组白细胞仍在正常范围水平,差异有统计学意义(P<0.05),治疗组血小板水平较对照组高,差异有统计学意义(P<0.05)。结论:艾灸督脉背部穴位用于晚期恶性肿瘤患者化疗后骨髓抑制的辅助治疗,有辅助粒细胞集落刺激因子升高白细胞的作用,且能使白细胞稳步上升并长期稳定在正常范围内,并且对血小板有迅速提升作用,用于化疗后白细胞下降及轻度血小板减少有良好的治疗作用,值得临床推广应用。
Objective: To observe blood index receiving herbs-partitioned moxibustion after chemotherapy in patients with malignant tumor. Method: 90 patients with leukopenia after chemotherapy of malignant tumors who were both spleen and kidney deficiency, were divided into two groups(45 cases every group). Treatment group received herbs-partitioned moxibustion on acupuncture point with subcutaneous injection of G-CSF 100 μg daily, and control group was injected G-CSF100 μg daily. The changes of blood indicators in patient were observed before and after treatment. Result: Five days after treatment, WBC was increased to the normal range in the control group, and was higher than the treatment group with statistically significant difference(P<0.05). Compared with the control group, platelet levels of the treatment group was increased with statistically significant difference(P<0.05). Ten days after treatment, leukopenia in control group was decreased, while white blood cells in the treatment group were still in the normal range. And the difference was statistically significant(P<0.05). Compared with the control group,platelet levels were higher in the treatment group with statistically significant difference(P<0.05). Conclusion: Herbs-partitioned moxibustion can be used as an adjuvant therapy for patients with malignant bone marrow suppression after chemotherapy. It can adjust granulocyte colony-stimulating factor in increasing white blood cells, increase white blood cells and keep the longterm stability steadily in the normal range, enhance platelets rapidly and has a good therapeutic effect in leukopenia and mild thrombocytopenia after chemotherapy. It is worthy of further clinical application.
出处
《中药与临床》
2013年第5期42-43,53,共3页
Pharmacy and Clinics of Chinese Materia Medica
关键词
督脉隔药灸
恶性肿瘤化疗
骨髓抑制
脾肾两虚
Herbs-partitioned moxibustion
chemotherapy in patients with malignant tumor
inhibition of bone marrow
deficiency of both spleen and kidney
