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基于GATE程序的MicroSPECT成像系统并行化Monte Carlo模拟 被引量:7

Parallel Monte Carlo simulation of MicroSPECT imaging system based on the GATE algorithm
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摘要 MicroSPECT(micro single photon emission computed tomography)是专用于小动物成像的分子核医学设备。为了准确研究复杂放射源分布条件下光子在MicroSPECT成像系统中的输运过程,使用GATE程序模拟了基于H8500位置灵敏光电倍增管和针孔准直器的MicroSPECT系统,并在清华高性能计算集群上实现了GATE程序的并行化模拟。通过并行计算有效地提高了模拟速度,分别获得了点源、线源、Derenzo模型、Moby模型的投影数据及用于迭代断层图像重建的系统点扩展函数(point spread function,PSF)数据。 MicroSPECT(micro single photon emission computed tomography) is a dedicated nuclear medicine device for small animal imaging.The transport of γ photons in the MicroSPECT imaging system was simulated for complicated radioactive source distributions for a MicroSPECT system with a H8500 position sensitive photoelectric multiplies tube and a pinhole collimator using the GATE programs.The parallelization of GATE simulation was run in parallel on the Tsinghua High Performance Computing Clusters,which effectively improved computational speed.The projection of the point source,the line sources,the Derenzo phantom,and the Moby phantom were acquired as well as the system point spread function(PSF) which are essential for iterative image tomographic reconstruction.
出处 《清华大学学报(自然科学版)》 EI CAS CSCD 北大核心 2007年第z1期928-932,共5页 Journal of Tsinghua University(Science and Technology)
基金 国家自然科学基金资助项目(10505012) 清华大学工程物理系基础研究基金项目
关键词 小动物成像 MicroSPECT(micro single PHOTON emission COMPUTED tomography) 并行计算 MONTE CARLO方法 small animal imaging MicroSPECT(micro single photon emission computed tomography) parallel computing Monte Carlo method
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参考文献5

  • 1[1]Santin G,Strul D,Lazaro D,et al.GATE,a Geant4-based simulation platform for PET and SPECT integratingmovement and time management[J].IEEE Trans Nucl Sci,2003,50:1516-1521. 被引量:1
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  • 3[3]Stolin A V,Majewski S,Williams M B,et al.Characterization of imaging gamma detectors for use in small animal SPECT[C]∥IEEE Nuclear Science Symposium Conference Record.Portland,Oregon USA:IEEE Press,2003:2085-2089. 被引量:1
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