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针对Ras蛋白法尼基转移酶的肿瘤靶向治疗 被引量:2

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出处 《癌症进展》 2004年第5期390-391,共2页 Oncology Progress
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同被引文献58

  • 1明学志,尹浩然,朱正纲,薛建元,王瑞年,林言箴.胃癌组织中H-ras和VEGF的表达与血管生成的关系及其临床意义[J].中华肿瘤防治杂志,2006,13(5):357-360. 被引量:8
  • 2Vogel C L,Cobleigh M A,Tripathy D,et al.Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer[J].J Clin Oncol,2002,20(3):719-726. 被引量:1
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  • 6Feldkamp M M,Lau N,Roncari L,et al.Isotype-specific Ras.GTP-levels predict the efficacy of farnesyltransferase inhibitors against human astrocytomas regardless of Ras mutational status[J].Cancer Res,2001,61 (10):4425-4431. 被引量:1
  • 7Johnston S R,Hickish T,Ellis P,et al.Phase Ⅱ study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor,R115777,in advanced breast cancer[J].J Clin Oncol,2003,21 (13):2492-2499. 被引量:1
  • 8Wherlock M,Gampel A,Futter C,et al.Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase[J].J Cell Sci,2004,117 (15):3221-3231. 被引量:1
  • 9Chen Z,Sun J,Pradines A,et al.Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice[J].J Biol Chem,2000,275(24):17974-17978. 被引量:1
  • 10Chun K H,Lee H Y,Hassan K,et al.Implication of protein kinase B/Akt and Bcl-2/Bcl-XL suppression by the farnesyl transferase inhibitor SCH66336 in apoptosis induction in squamous carcinoma cells[J].Cancer Res,2003,63(16):4796-4800. 被引量:1

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