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短暂性脑缺血发作对脑缺血耐受的影响 被引量:1

The Effect of Transient Ischemic Attack on Cerebral Ischemic Tolerance
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摘要 目的探讨短暂性脑缺血发作(TIA)在脑缺血耐受方面的临床意义。方法选择30例TIA后72h内发生脑梗死的患者为试验组(TIA组),并随机选择30例无TIA史的脑梗死患者作对照组。结果TIA组和脑梗死组在脑梗死体积、治疗前与治疗后15d,30d,90d的欧洲卒中量表(ESS)评分方面存在统计学差异(8.2mlvs10.6ml;62±22vs58±24;70±28vs66±32;80±20vs76±24;82±18vs77±23;P均<0.05)。结论TIA后发生脑梗死对减轻脑细胞损伤有一定临床意义。 Objective To analyze the effect of transient ischemic attack(TIA)on cerebral ischemic tolerance.Methods Total 60 cases with cerebral infarction enrolled in our investigation,in which 30 cases had TIA within 72 hours as TIA group and 30 cases had no TIA history as control group.Results The TIA group had less cerebral infarction volume than control group(8.2ml vs 10.6 ml,P<0.05),and had higher scores in European stroke scale(ESS)before treatment and after 15d,30d,90d treatment(62±22 vs 58±24,P<0.05;70±28 vs 66±32,P<0.05;80±20 vs 76±24,P<0.05;82±18 vs 77±23,P<0.05).Conclusion TIA may improve cerebral ischemic tolerance and it has definite clinical significance for decreasing the injury of brain cells in cerebral infarction.
作者 杨传军 范玲
出处 《中国卒中杂志》 2007年第12期979-981,共3页 Chinese Journal of Stroke
关键词 短暂性脑缺血发作 脑梗死 脑缺血耐受 Transient ischemic attack Cerebral infarction Cerebral ischemic tolerance
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  • 1Kitagawa K, Matsumoto M, Tagaya M, et al. Ischemic tolerance phenomenon found in the brain. Brain Res, 1990,528:21. 被引量:1
  • 2Yanamoto H, Mizuta I, Nagata I, et al. Infarct tolerance accompanied enhanced BDNF-Iike immunoreactivity in neuronal nuclei. Brain Res,2000,877:331. 被引量:1
  • 3Glazier SS, O' Rourke DM, Graham DI, et al. Induction of ischemic tolerance following brief focal ischemia in rat brain. J Cereb Blood Flow Metab, 1994,14 : 545. 被引量:1
  • 4Bederson JB, Pitts LH, Tsuji M, et al. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke, 1986,17:472. 被引量:1
  • 5Swanson RA, Morton MT, Tsao-Wu G, et al. A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab, 1990,10:290. 被引量:1
  • 6Chen J, Graham SH, Zhu RL, et al. Stress proteins and tolerance to focal cerebral ischemia. J Cereb Blood Flow Metab, 1996,16:566. 被引量:1
  • 7Stephenson DT, Schober DA, Smalstig EB, et al. Peripheral benzoliazepine receptors are colocalized with activated microglia following transient global forbrain isehemia in the rat. J Neurosei, 1995,15:5263. 被引量:1
  • 8Petito CK, Halaby IA. Relationship between ischemic neuronal necrosis to astrocyte expression of glial gibrillary acidic protein. Int J Dev Neurosci,1993,11 : 239. 被引量:1
  • 9Garcia-Pastor A, Diaz-Otero F, Castano-Garcia B. et al. Transient ischemic attacks: risk factors, duration and neuroimaging in a series of 173 patients. Rev Neurol,2002,35:107-110. 被引量:2
  • 10Kuhl DE, Edwards RQ, Ricci AR, et al. The Mark IV system for radionuclide computed tomography of the brain. Radiology,1976,121:405-413. 被引量:2

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