摘要
目的探讨儿童艾滋病临床特点。方法66例儿童艾滋病入选该研究,男46例,女20例,平均年龄8.7岁(2～16岁)。回顾分析其人口学资料、流行病学资料、临床表现及实验室检查结果。结果HIV感染确诊年龄2～15岁,平均7.7岁。通过母婴传播感染48例(72.7%),通过输血或血制品感染14例(21.2%),感染途径不明4例(6.1%)。常见的临床表现如下:体重下降43例(65.2%)、贫血42例(63.7%),持续或反复发热40例(60.6%)、疲乏感38例(57.6%)、皮疹31例(47.0%)、慢性或反复咳嗽28例(12.1%)、慢性腹泻24例(36.4%)、神经系统受累16例(24.2%)、鹅口疮13例(19.7%)、肝脾大12例(18.2%)。体格生长评价显示,身高和体重处于下等的分别有30例(45.4%)和26例(39.4%)。免疫功能均受抑制,重度抑制59例(89.4%),中度抑制7例(10.6%)。结论儿童HIV感染途径以母婴传播为主,临床表现多样,免疫系统显著受抑制。
Objective To study the clinical features of pediatric acquired immunodeficienecy syndrome(AIDS).Methods The epidemiological,clinical and laboratory data of 66 children with AIDS were retrospectively studied.Results Of the 66 patients,46(69.7%)were male and 20(30.3%)were female,with a mean age of 8.7 years(ranged 2-16 years).The mean age at diagnosis was 7.7 years(ranged 2-15 years).Vertical transmission as the route of infection was documented in 48 cases(72.7%).Fourteen children(21.2%)were infected through...
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2009年第2期93-95,共3页
Chinese Journal of Contemporary Pediatrics
基金
国家"十五"攻关项目(2004BA719A11)
