摘要
目的:研究紫杉醇(PTX)与表阿霉素(EPI)联合应用治疗晚期乳腺癌的疗效和毒副反应。方法:采用PTX135mg/m2,静脉滴入3h,d1;EPI50mg/m2,静脉滴入,d2;21天为1周期,6周期为1疗程。结果:总有效率为55.6%,中位疾病无进展时间11个月,毒副反应以骨髓抑制、过敏反应、心脏毒性、感觉神经毒性为主,无Ⅳ度毒副反应。结论:PTX、EPI联合应用治疗晚期乳腺癌疗效肯定,毒副反应能耐受。
Objective:To study the response and toxicity of the regimen of Paclitaxel combined with Epirubicin(PA regimen) in the treatment of advanced breast cancer.Methods:PA regimen: Paclitaxel 135mg/m2,3 hours iv drop d1;Epirubicin 50mg/m2,iv drop d2 and repeated every 21 days,6 cycles was a course.Results: The total response rate was 55.6 %,and the median time to progress was 11 months.The mian side effects were bone marrow suppression,anaphylactic response,cardiac toxicity and neuroseusory toxicity.There was no t...
出处
《现代肿瘤医学》
CAS
2008年第11期1928-1930,共3页
Journal of Modern Oncology
关键词
晚期乳腺癌
化学疗法
紫杉醇
表阿霉素
advanced breast cancer
chemotherapy
Paclitaxel
Epirubicin
