摘要
目的分离牛心朴子草中的活性成分。方法以牛心朴子草为原料,采用AB-8大孔吸附树脂分离牛心朴子草提取液中的活性成分,利用柱层析、重结晶等方法对活性部分进行分离和纯化。结果对分离得到的化合物采用质谱、红外光谱、紫外光谱和核磁共振谱图进行了表征,证实为7-脱甲氧基娃儿藤碱。结论AB-8大孔吸附树脂可以用于牛心朴子草活性成分的分离。
OBJECTIVE To separate active constituent from Cynanchum Komarovii.METHODS Cynanchum Komarovii Al.Iljinski was used as the raw material to separate active constituent with AB-8 macroporous resin.The active constituents were further separated and purified by column chromatography and rescrystallization.RESULTS The separated compounds were identified by means of MS,IR,UV and NMR spectral analysis and the active constituent was comfirmed to be 7-demethoxylophorine.CONCLUSION AB-8 macroporous resin can be used f...
出处
《华西药学杂志》
CAS
CSCD
北大核心
2008年第4期450-451,共2页
West China Journal of Pharmaceutical Sciences
