摘要
Objective:To explore the clinical significance of serum tumor markers and cytokines in the detection of breast cancer.Methods:A total of 586 different breast cancer staging, 250 patients with benign breast disease and 250 controls were detected and compared the serum tumor markers (CA125, CA153, CA199, CEA,β-hCG, CYFRA21-1, TPS) and cytokines (TNF-α, IL-6, IL-8, GDF3) level.Results:The serum tumor staging of breast cancer were different markers (CA125, CA153, CA199, CEA,β-hCG, CYFRA21-1, TPS) and cytokines (TNF-α, IL-6, IL-8, GDF3) were higher than those in control group and benign breast disease group and had statistical difference, serum tumor between different groups of breast cancer staging markers and cytokine levels were statistically different, with the staging of elevated serum tumor markers were increased with stage IV breast cancer group was the highest, was found between the control group and the benign breast disease group serum tumor marker was found the difference and cytokine.Conclusion:Serum tumor markers (CA125, CA153, CA199, CEA,β-hCG, CYFRA21-1, TPS) and cytokines (TNF-α, IL-6, IL-8, GDF3) in breast cancer detection have important clinical significance.
基金
Natural Science Foundation of Liaoning Province(Grant 201511290).
