摘要
目的优选复方大黄净化液提取工艺。方法基于复方大黄净化液组方原则,兼顾大黄酸、芦荟大黄素、大黄素甲醚、大黄素、大黄酚主要指标成分含量和干浸膏收率,以加水倍数、浸泡时间、提取时间和提取次数为考察因素,采用正交试验优选复方大黄净化液提取工艺条件。结果制剂最佳提取工艺为加水量为10倍量,浸泡30 min,提取时间1 h,提取次数3次。结论该方法有效的优选出复方大黄净化液提取工艺,工艺合理稳定,操作易行。
Objective To optimize extracting techniques of compound Dahuangjinghua liquid.Methods Based on compound Dahuangjinghua liquid formula principle,take the aloe-emodin,rhein,emodin,methyl ether,emodin,rhubarb phenol main index component content and water-soluble total Fried,with multiple water,soaking time,extracting time and extracting times to examine factors,optimizing compound rhubarb purification liquid extraction process by orthogonal experiment.Results The best condition is soaking 30 minutes,extracting 1 hour,extracting for 3 times,to add ten times of water.Conclusion The method is ef ective optimized compound Dahuangjinghua liquid extraction process,reasonable process stability,and easy to operate.
作者
韦振源
龚敏阳
莫小林
陈晓明
WEI Zhen-yuan;GONG Min-yang;MO Xiao-lin;CHEN Xiao-ming(The First Affiliated Hospital of Guangxi University of TCM,Nanning 530023,Guangxi,China)
基金
广西中医药大学立项课题(P2012093)
广西中医药大学第一附属医院青年基金立项课题(GZYQJ2012001)。
关键词
复方大黄净化液
正交试验
提取工艺
Compound Dahuangjinghua liquid
Orthogonal experiment
Extraction technology
