摘要
我国炎症性肠病的发病率逐年增高,其确切的病因尚不明确,研究表明肠道微生态在其中起到重要的作用.肠道微生态与炎症性肠病的相互作用成为近年来研究的热点.本文根据国内外有关炎症性肠病与肠道微生态方面的研究进展,从肠道微生态的概述、遗传易感性、疾病分型、炎症性肠病的微生态治疗和未来的研究方向等5个方面进行总结和述评.
The incidence of inflammatory bowel disease(IBD)is increasing year by year in China,but the exact cause of IBD is still unclear.In recent years,the interaction between intestinal microecology and IBD has become a hot topic and it has been verified that intestinal microecology plays an important role in the pathogenic mechanism of IBD.Based on the research progress of IBD and intestinal microecology at home and abroad,this article summarizes and comments on the five aspects,including the introduction of intestinal microecology,genetic susceptibility,diseases typing,treatment,and the direction of future research.
作者
万健
张玉洁
贺娜
吴开春
Wan Jian;Zhang Yujie;He Na;Wu Kaichun(Xijing Hospital of Digestive Diseases,Air Force Military Medical University,Xi′an 710032,China)
出处
《中华炎性肠病杂志(中英文)》
2019年第3期177-181,共5页
Chinese Journal of Inflammatory Bowel Diseases
基金
国家重点研发计划(2017YFC0908300)
国家自然科学基金(81421003、81627807).
关键词
炎症性肠病
肠道微生态
肠道菌群
Inflammatory bowel disease
Intestinal microecology
Gut microbiota