摘要
目的分析胃溃疡(GU)脾胃气虚证患者采用四君子汤加减联合艾灸疗法治疗的效果.方法选取2020年1月—2023年1月曹县人民医院收治的82例GU脾胃气虚证患者为研究对象,按随机数字表法将其分为对照组及观察组.对照组(n=41)采用艾灸疗法治疗,在此基础上,观察组(n=41)采用四君子汤加减治疗.比较两组患者的中医证候积分、症状消失时间、血清炎症因子水平及溃疡愈合率.结果治疗后,观察组的中医证候积分为(16.43±3.48)分,低于对照组(19.76±3.31)分,差异有统计学意义(P﹤0.05).观察组的餐后饱腹感、早饱、上腹痛、嗳气消失时间分别为(1.46±0.25)d、(1.67±0.43)d、(2.05±0.62)d、(2.45±0.83)d,均短于对照组的(1.88±0.43)d、(1.96±0.48)d、(3.63±0.73)d、(3.66±0.91)d,组间差异有统计学意义(P﹤0.05).治疗后,观察组的白细胞介素-6、肿瘤坏死因子-α、转化生长因子-β1水平分别为(106.33±23.16)ng/mL、(51.64±6.67)pg/mL、(1.02±0.15)pg/mL,均低于对照组的(154.56±35.67)ng/mL、(63.54±7.35)pg/mL、(1.57±0.67)pg/mL,组间差异有统计学意义(P﹤0.05).观察组的溃疡总愈合率为90.24%,高于对照组的70.73%,差异有统计学意义(P﹤0.05).结论GU脾胃气虚证患者采用四君子加减与艾灸疗法治疗的效果显著,可快速缓解症状,减轻机体炎症反应,提升溃疡总愈合率,值得推广.
Objective To analyze the effect of modified Sijunzi Decoction combined with moxibustion therapy on gastric ulcer(GU)with spleen and stomach Qi deficiency syndrome.Methods 82 GU patients with spleen and stomach Qi deficiency syndrome admitted to Cao County People's Hospital from January 2020 to January 2023 were selected as the study objects and were divided into a control group and an observation group according to random number table method.The control group(n=41)was treated with moxibustion therapy,on this basis,the observation group(n=41)was treated with modified Sijunzi Decoction.The TCM syndrome score,symptom disappearance time,serum inflammatory factor levels and ulcer healing rate were compared between the two groups.Results After treatment,the TCM syndrome score of the observation group was(16.43±3.48)points,which was lower than(19.76±3.31)points of the control group,and the difference was statistically significant(P﹤0.05).The disappearance time of satiety,early satiety,upper abdominal pain and belch after meals in the observation group were(1.46±0.25)d,(1.67±0.43)d,(2.05±0.62)d and(2.45±0.83)d,respectively,which were shorter than(1.88±0.43)d,(1.96±0.48)d,(3.63±0.73)d,(3.66±0.91)d in the control group,and the differences between the groups were statistically significant(P﹤0.05).After treatment,the levels of interleukin-6,tumor necrosis factor-αand transforming growth factor-β1 in the observation group were(106.33±23.16)ng/mL,(51.64±6.67)pg/mL,and(1.02±0.15)pg/mL,respectively,which were lower than(154.56±35.67)ng/mL,(63.54±7.35)pg/mL,(1.57±0.67)pg/mL in the control group,and the differences between the groups were statistically significant(P﹤0.05).The total healing rate of ulcer in the observation group was 90.24%,higher than 70.73%in the control group,and the differences were statistically significant(P﹤0.05).Conclusion The effect of modified Sijunzi Decoction combined with moxibustion therapy on GU patients with spleen and stomach Qi deficiency syndrome is remarkable,which can q
作者
朱精琪
ZHU Jingqi(Department of Traditional Chinese Medicine,Cao County People's Hospital,Heze Shandong,274400,China)
出处
《反射疗法与康复医学》
2024年第1期57-60,共4页
Reflexology And Rehabilitation Medicine
关键词
胃溃疡
脾胃气虚证
四君子汤加减
艾灸疗法
中医证候积分
炎症因子
Gastric ulcer
Spleen and stomach Qi deficiency syndrome
Modified Sijunzi Decoction
Moxibustion therapy
TCM syndrome score
Inflammatory factors
