摘要
目的研究探讨卵巢癌早期诊断中采用彩超联合CA125、HE4、AFP的临床价值。方法2019年5月-2020年5年期间抽选院内收治68例卵巢肿瘤患者为分析样本,经病理诊断确诊卵巢良性肿瘤42例,卵巢癌26例,全部患者均行彩超检查及血清CA125、HE4、AFP检查,分析具体检查结果。结果彩超联合CA125、HE4、AFP应用于早期卵巢癌诊断灵敏度为(40/45)88.9%、特异度为(21/23)91.3%、准确度为(61/68)89.7%;卵巢良性肿瘤与卵巢癌经彩色多普勒超声检查可见形态、质地、位置、血流等存在显著差异;卵巢良性肿瘤与卵巢癌血清CA125、HE4、AFP存在显著差异(P<0.05)。结论卵巢癌早期诊断中采用彩超联合CA125、HE4、AFP临床价值突出,可全面推广。
Objective To investigate the clinical value of color doppler ultrasound combined with CA125,HE4 and AFP in the early diagnosis of ovarian cancer.Methods From May 2019 to May 2020,68 patients with ovarian tumor were selected for analysis.42 patients with benign ovarian tumor and 26 patients with ovarian cancer were diagnosed by pathology.All patients were examined by color doppler ultrasound and serum CA125,HE4 and AFP,analysis of specific test results.Results The diagnostic sensitivity(40/45),specificity(21/23)and accuracy(61/68)of color doppler ultrasound combined with CA125,HE4 and AFP were 88.9%,91.3%and 89.7%,respectively There were significant differences in morphology,texture,location and blood flow between benign ovarian tumor and ovarian cancer by Color Doppler ultrasonography,and there were significant differences in serum CA125,HE4 and AFP between Benign Ovarian Tumor and ovarian cancer(P<0.05).Conclusion The application of Color doppler ultrasound combined with CA125,HE4 and AFP in the early diagnosis of ovarian cancer is of great clinical value and can be generalized.
作者
赵金武
刘文华
闫若谷
ZHAO Jin-wu;LIU Wen-hua;YAN Ruo-gu(Jilin Oilfield Hospital,Jilin Songyuan 138000,China)
出处
《实用妇科内分泌电子杂志》
2020年第18期1-1,11,共2页
Electronic Journal of Practical Gynecological Endocrinology
