摘要
目的:探讨应用扩散加权成像(DWI)的表观弥散系数(ADC值区分前列腺癌T分期高危组与低危组的价值。方法:收集2016年1月-2018年4月217例前列腺癌患者的病例资料进行研究。所有患者均在GE3.0T磁共振上获得图像,图像序列包含横轴位高分辨率T2WI、DWI(b=0、1000、2000、3000 s/mm2),所有病例均有手术病理结果。由两名10年以上有前列腺疾病诊断经验的放射科医师分别对病灶进行ADC值的测量,并进行一致性和可重复性分析;对前列腺癌T分期高危组与低危组间的ADC值进行比较;利用ROC曲线对使用不同b值的ADC值区分前列腺癌T分期高、低危组的效能进行评价。结果:前列腺癌病灶ADC值的一致性和可重复性极好,前列腺癌T分期高危组与低危组间ADC值有明显差别(P<0.05)。不同b值的ADC值能够区分T分期的高危组和低危组,但其效能无明显差别。结论:DWI的ADC值对区分前列腺癌T分期高低危组有一定帮助,可以在临床上起到辅助诊断的作用。
Objective:To investigate the value of ADC value in distinguishing high risk group and low risk group of T staging of prostate cancer.Methods:217 eligible prostate cancer patients from January 2016 to April 2018 were enrolled in the study.The images of all patients were obtained on GE 3.0 T MRI.The image sequences included axial high resolution T2 WI and DWI(b=0,1000,2000 and 3000 s/mm2).The postoperative pathological results were obtained in all cases.The ADC values of prostate cancer lesions were measured by two prostate diagnostic physicians with more than ten-year experience,and consistency and repeatability analysis were done.The ADC values between high risk group and low risk group of T stage of prostate cancer were compared.The ROC curve was used to evaluate the ability of ADC values of different b values to distinguish the high and low risk groups of T stage of prostate cancer.Results:The consistency and repeatability of the ADC values of prostate cancer lesions measured by two physicians were excellent.There was significant difference in T stage of prostate cancer between high risk group and low risk group(P<0.05).The ADC value of different b value could distinguish the high and low risk groups of prostate cancer,but there was no significant difference in efficiency.Conclusions:ADC values provided some help for the judgment of high and low risk group of T stage of prostate cancer.ADC values between the two groups were statistically different.
作者
张洪涛
俞鸿凯
郭勃毅
王海屹
白旭
叶慧义
ZHANG Hongtao;YU Hongkai;GUO Boyi;WANG Haiyi;BAI Xu;YE Huiyi(Department of Radiology,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China;Department of Radiology,the Fifth Medical Centre,Chinese PLA General Hospital;Department of Urology,the First Medical Center of Chinese PLA General Hospital;Magnetic Room,People's Hospital of Qian'an City)
出处
《微创泌尿外科杂志》
2021年第1期55-60,共6页
Journal of Minimally Invasive Urology
基金
国家自然科学基金面上项目(81771785)
关键词
前列腺癌
T分期
扩散加权成像
表观弥散系数
prostate cancer
T staging
diffusion weighted imaging
apparent diffusion coefficient
