摘要
目的探讨口咽部畸胎瘤的临床特征及诊治方法。方法回顾性分析1例青少年口咽部畸胎瘤患者的临床资料并结合国内外相关文献进行分析探讨。结果检索获得1980年至2023年国内外发表的共45篇文献,加上本例患者共纳入56例口咽部畸胎瘤。该组口咽部畸胎瘤患者大多于新生儿出生时即发现,病变部位以软腭及扁桃体为主,女性多于男性,部分患者伴有其他部位畸形,以腭裂最多见,病理分型以成熟型畸胎瘤为主,大部分可经口切除,预后良好。结论口咽部畸胎瘤大多为成熟畸胎瘤,属良性病变,以新生儿及婴幼儿多见。高分辨率CT联合MRI检查有助于明确诊断及病变范围,血清AFP检测术前可帮助判断良恶性,术后可用于疗效观察及预后判断。手术是切除口咽部畸胎瘤的首选治疗方法,早期切除者预后良好,术后需定期随访。
Objective To explore the clinical characteristics,diagnosis and treatment of oropharyngeal teratoma.Methods A retrospective analysis was conducted on the clinical data of a teenage patient with oropharyngeal teratoma,and relevant literature published in Chinese and English was analyzed and discussed.Results A total of 45 articles published domestically and internationally from 1980 to 2023 were retrieved,and a total of 56 cases of oropharyngeal teratomas were retrieved,including this case.Most of the 56 cases of oropharyngeal teratomas were discovered at birth,mainly in the soft palate and tonsils,with more females than males.Some patients had deformities in other areas,with cleft palate being more common.The pathological classification was mainly mature teratomas,most of which could be removed through the mouth,and the prognosis was good.Conclusion Most oropharyngeal teratomas are benign lesions,which are more common in newborns and infants.High resolution CT combined with MRI can help clarify the diagnosis and lesion range,and serum AFP testing can help determine whether it is benign or malignant before surgery,and can be used for efficacy observation and prognosis assessment after surgery.Surgery is the preferred treatment method for removing oropharyngeal teratomas.Early resection has a good prognosis,and regular follow-up is required after surgery.
作者
马静
张敏
朱歆洁
MA Jing;ZHANG Min;ZHU Xinjie(Department of Otorhinolaryngology,The First Affiliated Hospital,Nanjing Medical University,Nanjing 210029,Jiangsu,China)
出处
《山东大学耳鼻喉眼学报》
CAS
2024年第2期89-97,共9页
Journal of Otolaryngology and Ophthalmology of Shandong University
关键词
畸胎瘤
口咽部肿瘤
青少年
软腭
扁桃体
腭裂
Teratoma
Oropharyngeal tumor
Adolescent
Soft palate
Tonsil
Cleft palate
