摘要
目的观察腹腔镜下保留睾丸动脉精索静脉高位结扎术联合麒麟丸治疗精索静脉曲张导致不育的临床疗效。方法将60例原发性精索静脉曲张不育患者随机分为治疗组和对照组,每组30例。对照组给予腹腔镜下保留睾丸动脉精索静脉高位结扎术治疗,治疗组给予腹腔镜下保留睾丸动脉精索静脉高位结扎术联合麒麟丸治疗。治疗3个月后检查患者精液,分析精液常规参数、精子DNA碎片率的变化情况,比较两组的疗效情况。结果治疗组患者治疗后精液密度为(40.63±11.37)×10~6/mL,前向运动精子率为(37.57±10.84)%,精子DNA碎片率为(14.48±8.93)%,临床总有效率为86.67%。对照组患者治疗后,精液密度为(28.77±10.68)×10~6/mL,前向运动精子率为(33.90±9.67)%,精子DNA碎片率为(18.33±9.27)%,临床总有效率为76.67%。治疗组与对照组相比,各项指标改善更为显著,差异有统计学意义(P<0.05)。结论腹腔镜下精索静脉保留睾丸动脉高位结扎术联合麒麟丸能提高精索静脉曲张不育患者的精液密度,改善精子活力,增加受孕率。
Objective To observe the clinical efficacy of laparoscopic high ligation of spermatic vein with preserved testicular artery combined with Qilin Pill in the treatment of male infertility caused by varicocele.Methods Sixty infertile patients due to primary varicocele were randomly divided into the treatment group and control group,30 cases in each group.The control group was treated with laparoscopic high ligation of spermatic vein with preserved testicular artery,and the treatment group was treated with laparoscopic high ligation of spermatic vein with preserved testicular artery combined with Qilin Pill.After treatment for 3 months,the changes of semen routine parameters and sperm DNA fragment rate were analyzed,and the efficacy was compared between the two groups.Results After treatment,the semen density of the patients in the treatment group was(40.63±11.37)×10~6/mL,the sperm rate of forward movement was(37.57±10.84)%,the sperm DNA fragment rate was(14.48±8.93)%,and the clinical total effective rate was 86.67%.After treatment,the semen density of the patients in the control group was(28.77±10.68)×10~6/mL,the sperm rate of forward movement was(33.90±9.67)%,the sperm DNA fragment rate was(18.33±9.27)%,and the clinical total effective rate was 76.67%.Compared with the control group,the improvement of all indicators in the treatment group was more significant,with statistically significant differences(P<0.05).Conclusion Laparoscopic high ligation of spermatic vein with preserved testicular artery combined with Qilin Pill can enhance the semen density of infertile patients due to varicocele,improve the sperm motility and increase the pregnancy rate.
作者
翟新宇
葛旻垚
赵建华
ZHAI Xinyu;GE Minyao;ZHAO Jianhua(Department of Urology Surgery,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
出处
《上海中医药杂志》
2020年第S01期110-112,共3页
Shanghai Journal of Traditional Chinese Medicine
